A-50 is a very drastic synthetic steroid, 17-alpha-alkylated modification of dihydrotestosterone. It was developed for the treatment of osteoporosis and anaemia, as well as to stimulate muscle gain in malnourished and debilitated patients.

By its performance parameters A-50 is most similar to Methandienone. As with Methandienone, A-50 provokes not only active muscle bulking, but also a significant increase in power performance. However, a large part of the gained weight is because of water retention in the body, which can lead to high blood pressure on cycle.

Thanks to its ability to influence the level of hemoglobin and to increase the blood volume in the body, A-50 may cause an extremely strong pumping effect by athletes, which consequently complicates the training process, because muscles get sore almost immediately after the first heavy set.

A-50 is a derivative of dihydrotestosterone, which gives it a chemical structure that does not aromatize. Despite the fact that A-50 does not directly convert to estradiol, it itself has pronounced estrogenic properties. It should be remembered that because of this peculiarity only antiestrogens would be able to combat with estrogenic side effects, but not aromatase inhibitors, because aromatase is not involved into the process.

Some suggest that A-50 estrogenic activity relates to the progestogenic one, like with Nandrolones. Side effects may be similar. However, medical studies have shown that Oxymetholone does not possess any progestogenic activity.